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Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune-mediated disorder of the peripheral nervous system that causes weakness, numbness and impaired function. At CNS Brain Center, we believe the future of CIDP management lies in early diagnosis, early intervention, and individualized, evidence-based care. In this blog we’ll explore the role of the EMG test and IVIG treatment in CIDP, and how our model accelerates access and improves outcomes.
The EMG test (electromyography) and associated nerve conduction studies are central to the diagnosis of CIDP. According to widely accepted guidelines, the diagnosis of CIDP requires a combination of clinical evaluation, electrodiagnostic testing (including EMG and nerve conduction studies) and supportive evidence.
In particular, for CIDP diagnosis, nerve conduction studies show anatomical evidence of demyelination: slowed conduction velocity, prolonged distal latencies, temporal dispersion, and conduction block. EMG/nerve conduction is thus a key piece of the puzzle. As one expert source states: “When done properly, the EMG nerve conduction study is the most important test in making the diagnosis of CIDP.”
Using an EMG test early can lead to early intervention with treatments such as IVIG, which may improve long-term outcomes.
Once CIDP diagnosis is made, the therapeutic focus comes into play. Among first-line options for CIDP treatment is IVIG treatment (intravenous immunoglobulin).IVIG works by providing antibodies that modulate the immune response, reducing the inflammation that attacks myelin in the peripheral nerves.
Clinical studies show that IVIG treatment leads to improvement in functional disability, often within weeks. For example, a systematic review found that IVIG improved disability in patients with CIDP compared to placebo.
Dosage guidelines frequently start with an induction dose of 2 g/kg over 2-5 days followed by maintenance dosing (e.g., 1 g/kg every 3 weeks). Side-effects are possible (renal impairment, thrombosis, headache, etc) but with appropriate monitoring the therapy is generally well tolerated.
In short: the EMG test enables diagnosis, and IVIG treatment offers a powerful, evidence-based therapy. Together they form the backbone of CIDP diagnosis and treatment.
With CIDP, delays in diagnosis and treatment can permit ongoing nerve damage (especially axonal degeneration) which leads to permanent deficits. That’s why the keyword “early intervention” is so important. Catching CIDP early via EMG test enables us to initiate IVIG treatment sooner, maximizing the chance for functional recovery.
At CNS Center, we emphasize shorter wait times to see a physician, faster scheduling of electrodiagnostic testing (EMG/nerve conduction), and rapid initiation of individualized IVIG treatment plans. Rather than a one-size-fits-all approach, we tailor care to the specific disease characteristics, patient comorbidities, and functional goals — true individualized care.
At CNS Center:
By accelerating diagnosis (via EMG test), enabling early intervention (via IVIG treatment) and offering individualized, evidence-based care, we position the CNS Center at the forefront of CIDP treatment in the Chicago area.
To learn more and schedule a consultation, visit CNS Center at www.cns-center.com.